Which viral manifestation is associated with AIDS?

Hairy leukoplakia is specifically associated with HIV/AIDS due to the immunocompromised state that results from the virus's attack on the immune system, particularly CD4 cells. This condition is caused by the Epstein-Barr virus (EBV), which can opportunistically manifest in those whose immune systems are weakened, such as in individuals with AIDS.

Herpes simplex virus (HSV), which causes oral and genital herpes, is also more frequently activated in individuals with AIDS. The combination of herpes infections and hairy leukoplakia serves as important clinical indicators of immune system failure due to HIV/AIDS.

In contrast, viral warts are primarily caused by the human papillomavirus (HPV) and are not specifically linked to the immunocompromised state associated with AIDS. Shingles, caused by the varicella-zoster virus, and cold sores, caused by herpes simplex virus type 1, can occur in anyone, though they may present more severely in those with weakened immune systems. However, they are not definitive indicators of AIDS in the way that hairy leukoplakia is. Thus, option B stands out as the correct answer in this context.